AUTO–MUTE

AUTOmated server for predicting...
      ...functional consequences of amino acid MUTations in protEins

tessellated_t4_lysozyme

 

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 Disease Potential of Human nsSNPs

Structural Bioinformatics at
George Mason University

Questions or Comments?
mmasso@gmu.edu

Disease Potential of Human nsSNPs

PDB ID
(e.g., 1EGC)

Chain
(use @ if null)

Mutation
(e.g., I53T)

Mutant #1

Mutant #2

Mutant #3

Mutant #4

Mutant #5


Classification Model: Random Forest (details)
Prediction: A human nsSNP in a coding region, causing a mutation in the corresponding protein structure, either has an association with disease or is simply a neutral polymorphism.